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Brightens uneven skin tone over time

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Fades dark spots & discoloration

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Supports collagen and skin repair

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Safe and painless to use at home

Excellent 4.8 | 1,465 Reviews

Salmon DNA Infusion System for Dark Spots

Visibly improve dark spots, sun spots, and uneven skin tone in just 5 minutes, twice a month.

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Helps visibly fade stubborn discoloration

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Delivers PDRN deep, without pain

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Gentle & suitable for sensitive skin

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Brighter-looking skin, zero downtime

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Feel the difference after your first treatment

Ships by: ...
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Safe • Painless • Gentle for sensitive skin

Maximize your results

Risk-Free 90-Day Guarantee

That's how confident we are in your results. But if you're not thrilled, send it back and we'll refund your purchase.

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Fragrance-Free

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Alcohol-Free

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No Artificial Colorants

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dermatologist
approved

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Non-Comedogenic

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Cruelty-Free

Trusted By Over 5,000 Customers

Rated “Excellent” based on 1,400+ reviews

Lucille DARK SPOTS.webp__PID:59833c27-f87d-4c92-8062-1df2c84201d3

Dark Spots & Uneven Skin Tone

Lucille B.

Verified Customer

  • Visibly reduce the appearance of dark spots
  • Brightens uneven-looking skin tone
  • Leaves skin looking smoother and more radiant
Susan.webp__PID:ac6cf2b5-7040-4167-88cf-be3e8423e3fa

Uneven Texture & Skin Radiance

Tamara J.

Verified Customer

  • Smooths the look of uneven skin texture
  • Improves visible brightness & radiance
  • Helps skin appear healthier and more refreshed
Traci DARK SPOTS.webp__PID:3c27f87d-1c92-4062-9df2-c84201d33349

Sun Damage & Skin Tone

Traci G.

Verified Customer

  • Reduces the look of sun spots & discoloration
  • Smooths the appearance of fine lines & texture
  • Supports a brighter, more even-looking complexion
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Glow & Uneven Skin Tone

Brianna B.

Verified Customer

  • Brightens dull, tired-looking skin
  • Improves uneven tone & discoloration
  • Refines texture for a naturally radiant glow
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Dark Spots & Skin Texture

Nichole H.

Verified Customer

  • Visibly softens dark spots & discoloration
  • Refines uneven-looking skin texture
  • Supports smoother, healthier-looking skin
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Texture & Post-Breakout Marks

Joe K.

Verified Customer

  • Smooths rough-looking skin texture
  • Improves the appearance of post-breakout marks
  • Supports a clearer, more even-looking complexion

Dark Spots Start Below the Surface. Most Products Never Reach Them.

Precision Micro-Infusion designed to help active ingredients absorb beyond the surface.

Most brightening serums sit on the surface of the skin, while harsher treatments can leave skin irritated and sensitive. We designed the Salmon DNA Infusion System to help bridge that gap.

Our 24K Gold Micro-Infusion Stamp creates ultra-fine micro-channels that help deliver PDRN (Salmon DNA) and active ingredients more effectively into the skin. Unlike traditional rollers that can drag or irritate the skin, our precision-stamped needles provide a gentle, controlled, and virtually painless experience.

By enhancing absorption and supporting the skin’s natural renewal process, the Salmon DNA Infusion System helps visibly improve dark spots, sun damage, dullness, and uneven tone over time — without harsh procedures or downtime.

94%

noticed smoother texture and better skin tone after treatments

91%

saw visible improvement in the appearance of post-acne scars

96%

said their skin felt healthier, firmer, and more hydrated

The Ingredients Behind Brighter, More Even-Looking Skin

KEY INGREDIENTS

PDRN (Salmon DNA)

A skin-replenishing ingredient known for supporting skin renewal, hydration, and a healthier-looking complexion — helping improve the appearance of uneven tone and dull skin over time.

Niacinamide

A multitasking vitamin that helps visibly brighten uneven skin tone, refine texture, and support a healthier skin barrier for a more radiant complexion.

Panthenol (Pro-Vitamin B5)

A soothing active that calms, nourishes, and helps skin maintain softness and resilience — ideal for mature or sensitive skin.

Hyaluronic acid

A deeply hydrating ingredient that helps skin look smoother, healthier, and more radiant while supporting lasting moisture balance.

FORMULATED WITHOUT: Artificial colorants, fragrance, alcohol, or comedogenic ingredients. Cruelty free.

VIEW FULL INGREDIENTS LIST.

Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen.

The Ingredients Behind Brighter, More Even-Looking Skin

KEY INGREDIENTS

PDRN (Salmon DNA)

A skin-replenishing ingredient known for supporting skin renewal, hydration, and a healthier-looking complexion — helping improve the appearance of uneven tone and dull skin over time.

Niacinamide

A multitasking vitamin that helps visibly brighten uneven skin tone, refine texture, and support a healthier skin barrier for a more radiant complexion.

Panthenol (Pro-Vitamin B5)

A soothing active that calms, nourishes, and helps skin maintain softness and resilience — ideal for mature or sensitive skin.

Hyaluronic acid

A deeply hydrating ingredient that helps skin look smoother, healthier, and more radiant while supporting lasting moisture balance.

FORMULATED WITHOUT: Artificial colorants, fragrance, alcohol, or comedogenic ingredients. Cruelty free.

VIEW FULL INGREDIENTS LIST.

Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen.

3 Simple Steps to Brighter, More Even-Looking Skin

Just 5 minutes every 2 weeks.

Every order comes with a step-by-step video guide and instructions.

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Prep Your Skin

Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.

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Attach & Prime

Twist the serum vial directly onto the microneedle head. Hold the device upside down for ~2 minutes to allow full serum flow into the needles.

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Stamp & Infuse

Gently press the device onto your skin, starting from the center of the face and moving outward with 50% overlap. Repeat 2–3 passes over problem areas.

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number-1.png__PID:887f6aa5-597e-402f-b2ed-178ed4d7b916

Prep Your Skin

Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.

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number-2.png__PID:7f6aa559-7ea0-4fb2-ad17-8ed4d7b916cf

Attach & Prime

Twist the serum vial directly onto the microneedle head. Hold the device upside down for ~2 minutes to allow full serum flow into the needles.

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Stamp & Infuse

Gently press the device onto your skin, starting from the center of the face and moving outward with 50% overlap. Repeat 2–3 passes over problem areas.

How It's Made

Inside Our FDA-Registered, GMP-Certified Production Facility

Our PDRN Micro-Infusion System is produced in an FDA-registered, GMP-certified facility using clean, controlled, and automated manufacturing processes. Every batch is tested to ensure safety, sterility, and consistent quality.

THE DRM LAB vs. Other Solutions.

Why Traditional Dark Spot Treatments Fall Short

Derm System Comparison
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Helps improve visible discoloration
Gentle on sensitive skin
Zero downtime
Supports brighter-looking skin
Helps active ingredients absorb more effectively
Safe for most skin tones
At-home treatment
Includes precision serum infusion
Complete system (nothing else to buy)
90-day money-back guarantee
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Brighter, More Even-Looking Skin.

Backed by a 90-Day Guarantee.

We know how frustrating stubborn dark spots and uneven skin tone can feel — especially after trying product after product with little visible change.

That’s why we created a gentler, more advanced approach designed to help support brighter, smoother, more radiant-looking skin over time.

Try the complete Salmon DNA Infusion System for 90 days. If you don’t see visible improvement, we’ll give you a full refund.

No questions asked.

GET BRIGHTER, MORE EVEN SKIN

90-Day Money Back

Free Express Shipping

TRUSTED BY THOUSANDS IMPROVING DARK SPOTS & UNEVEN SKIN TONE

Results That Speak for Themselves

Melanie DARK SPOTS.webp__PID:833c27f8-7d1c-42c0-a21d-f2c84201d333

Finally something that actually works!

“I’ve tried so many dark spot serums over the years, but nothing really made a visible difference. After using this consistently, my skin started looking brighter, smoother, and more even overall. The biggest difference is how healthy and fresh my skin looks now without makeup.”

Melanie G.

Verified Customer

- from United States

Purchased: 3 Month Supply

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Didn’t expect this much progress

“I wasn’t expecting dramatic results overnight, but after a few treatments I noticed my complexion looked more even and glowy. Some of my dark spots and scars started fading and my skin texture looked smoother too.”

Aaron A.

Verified Customer

- from United States

Purchased: 5 Month Supply

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The glow is what surprised me most

“I originally bought this for uneven tone and dark spots, but what really surprised me was how much healthier and brighter my skin looked overall. My makeup sits better and my skin feels smoother after every treatment.”

Maria I.

Verified Customer

- from United States

Purchased: 3 Month Supply

Still Got Questions?

Our customer reviews

Customer Reviews
4.8
★★★★★
Based on 1.465 reviews
★★★★★
1147
★★★★☆
271
★★★☆☆
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13
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Emily

Verified Buyer

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United States

Finally seeing brighter, healthier-looking skin

I’ve spent years trying different brightening serums and treatments for uneven skin tone, but nothing ever made a visible difference long term. I’m on my 9th treatment now and my skin finally looks smoother, brighter, and more even overall. Even my husband noticed my skin looked healthier before I mentioned anything. It feels gentle, easy to use, and honestly something I actually look forward to now.

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Sarah

Verified Buyer

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United States

My skin finally looks more even

I’m in my 30s and while my breakouts are mostly gone, I was still dealing with uneven tone and lingering dark spots on my cheeks. I’ve tried so many products over the years — serums, masks, exfoliants — but nothing really changed how my skin looked overall.I started using this every other week about two months ago and my skin feels completely different. It looks smoother, brighter, and more radiant. What I love most is how simple the whole process is. 5 minutes, no irritation, and my skin always looks refreshed afterward.

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Jessica

Verified Buyer

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United States

THE REAL AMAZING PRODUCT

I’ve struggled with uneven tone and discoloration for years and this is the first product where I’m seeing gradual but real improvement. It’s not an overnight transformation, but after about 5 treatments my skin tone looks more even and my complexion looks noticeably brighter. I finally feel like my skin is moving in the right direction.

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Kevin

Verified Buyer

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United States

Love!

Just started using it and honestly I’m surprised by how gentle it feels. No stinging, irritation, or major redness afterward. I’m only two sessions in so I haven’t seen dramatic changes yet, but my skin definitely feels smoother and looks more refreshed after each treatment. Excited to keep going.

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Ashley

Verified Buyer

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United States

Worth the wait

I didn’t notice major changes immediately, but around the 5th treatment my skin suddenly started looking smoother and more radiant overall. Some of my dark spots looked lighter and my complexion felt more even. It’s not a miracle fix overnight, but it absolutely feels worth sticking with.

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Jack

Verified Buyer

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United States

My skin looks smoother already

I’ve always dealt with uneven texture and discoloration on my cheeks. After about 2 months, my skin already looks smoother and brighter — especially on the left side of my face where I had more visible uneven tone. Looking forward to seeing the progress continue over the next month.

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Tasha

Verified Buyer

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United States

So glad I gave this a try

I’ve spent hundreds on facials, peels, and other skin treatments over the years, and honestly this has been one of the easiest routines to stay consistent with. After about 3 sessions I started noticing my skin looked brighter and smoother overall. My complexion looks healthier now and I’m so happy I decided to stick with it.

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Luis

Verified Buyer

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United States

Way better than I expected

I honestly didn’t expect much at first, but I’ve been really impressed. My skin tone looks more even, my complexion feels smoother, and my skin overall just looks healthier. The instructions were super clear too, which made the whole process easy from the start.

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Sophia

Verified Buyer

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United States

Visible improvement, but consistency matters

I’ve used the system 5 times now and my skin definitely looks smoother and more even overall. Some of my older dark spots are starting to look lighter too. It’s not an overnight transformation, but I do think it works if you stay consistent with it. Only reason it’s not 5 stars is there was a slight learning curve during the first treatment.

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Daniel

Verified Buyer

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United States

Skin feels better

I’m on week 7 now and while I haven’t seen dramatic fading yet, my skin overall feels smoother and looks healthier. The uneven tone on my cheeks has started improving slowly too. I think this is definitely more of a gradual-results product, but so far I’m encouraged. The serum itself feels really nice on the skin.

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Alina

Verified Buyer

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United States

Worth sticking with

Let’s be honest — this isn’t instant. You really have to stay consistent with it. But after about 6 weeks, I can say my skin tone looks more even and my complexion overall looks brighter and smoother. Some darker spots are still there, but they already look softer than before. I’m excited to keep going.

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Vanessa

Verified Buyer

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United States

Gentle and easy

So far this is the only skin treatment I’ve tried that hasn’t irritated my skin or caused breakouts afterward, which is a huge plus for me. I do feel like my skin looks brighter and smoother already, just not quite as quickly as I hoped. I also wish there was a little more guidance around how much pressure to use at first, but once I figured it out the process became really easy.

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Rachel

Verified Buyer

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United States

Finally something my skin actually tolerates

Absolutely love this product, I can see my skin plump as I put it on! Definitely seeing less wrinkles! Highly recommend!!

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Leo

Verified Buyer

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United States

Really impressed so far

I purchased a few treatments a couple weeks ago and have only used it once so far, but I’m already impressed with how easy and comfortable the whole process is. No real discomfort or irritation afterward. Obviously it’s too early to talk about major results yet, but I’m excited to keep using it and see how my skin improves over time.

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Alex

Verified Buyer

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United States

Still early, but liking it so far

Started using the system about 2 weeks ago. The process is easy and my skin always feels smoother and more refreshed afterward. I haven’t noticed major changes in my dark spots yet, but I know these things take time. Planning to stay consistent and see how my skin looks after a few more treatments.

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Vanessa

Verified Buyer

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United States

No big difference yet

I’ve used it 3 times so far. I do like how soft and hydrated my skin feels after each treatment, but I haven’t seen major fading in my dark spots yet. Maybe I just need more time and consistency. Hoping to start seeing more visible improvement soon.

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Heather

Verified Buyer

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United States

Good quality, still waiting on bigger results

The product itself feels really high quality and I love that it feels more hygienic and gentle than traditional rollers. So far my skin definitely feels smoother and looks more refreshed after treatments, but I haven’t seen the level of improvement I was hoping for yet. I’m going to continue using it for another month or two before fully deciding.

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Diego

Verified Buyer

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United States

Slight redness after use

I followed all the instructions and the treatment itself was easy to do, but my skin does get a little red and dry for about a day afterward. It’s not severe, but definitely noticeable on my skin. I’m hoping it improves as my skin adjusts because overall I like how smooth my skin feels after using it.

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Samira

Verified Buyer

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United States

Mixed feelings

I really wanted to love this because I like how simple and gentle the routine is. I think I was expecting faster results after reading some of the reviews online. My skin does look smoother and more hydrated after treatments, but my uneven tone hasn’t improved as much as I hoped yet. Maybe I just need to give it more time.

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Julia

Verified Buyer

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United States

It’s fine so far

I don’t dislike the product at all, but I’m still waiting to see more noticeable changes. The good thing is it hasn’t irritated my skin whatsoever, which is rare for me. My skin feels softer and looks a little brighter after treatments, but I think it’s still too early for me to fully judge the long-term results.

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Sarah

Verified Buyer

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United States

Improved a little bit

I felt my skin texture has improved.

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Brian

Verified Buyer

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United States

I'm hopeful

I honestly haven’t noticed much difference in my uneven skin tone yet, but I know I’m still early into the process. The treatments are easy to do and feel gentle on my skin, so I’m planning to continue using it a bit longer before deciding.

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Brittany

Verified Buyer

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United States

It’s too early to tell

I’ve only used it twice since receiving it, so I think it’s still too early to really tell how effective it will be. So far my skin feels softer and more hydrated after treatments, but I haven’t seen major visible improvement in my dark spots yet. Looking forward to seeing how things progress over the next few weeks.

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Felicia

Verified Buyer

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United States

I'll try more time

For me the results are coming slowly, but I do think my skin already looks a little smoother and more even than before. I haven’t seen dramatic fading yet, but I’m going to continue using it longer and see how my skin improves with more treatments.

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Melissa

Verified Buyer

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United States

Waiting for the delivery

I bought 3 kits but I never received them due to lost package. They shipped new ones to me, still waiting to try them

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Eric

Verified Buyer

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United States

Maybe too soon

Only done two treatments so far. Nothing bad to say but nothing good either. I guess I just need to keep going and be patient.

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Valerie

Verified Buyer

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United States

Missing my delivery!

I have not received my order ! Can I get a refund!!!

>> THE DRM LAB replied:
Thank you for reaching out. We have been trying to contact you since June 27 after DHL notified us of a delivery attempt, but we did not receive a response to our messages. Our email support team will send you another message regarding this concern. Thank you.

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John

Verified Buyer

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United States

Received wrong item

I received the wrong item!! Why? please ship me the correct one

>> THE DRM LAB replied:
Hi John, we apologize for the incovenience. We already shipped the correct item to you. Thank you for your patience.

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Jessica

Verified Buyer

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United States

Don’t see the hype about it

I have used it for three weeks now and have not noted any difference. Even on the day off I don’t think it is effective at all. The price for the tool is not justifiable. It’s quite disappointing. I’ll continue using it and hopefully I’ll be wrong.

>> THE DRM LAB replied:
Hi Jessica! Thank you for sharing your honest feedback. We completely understand that waiting for visible skin changes can feel frustrating, especially when dealing with stubborn discoloration and uneven skin tone.Skin renewal and visible brightening often take consistency and time, especially with gradual treatments like micro-infusion. Many users begin noticing more visible improvement between the 8th and 12th week of consistent use.We truly appreciate your patience and we’re always here if you need help optimizing your routine or have any questions along the way.

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Layla

Verified Buyer

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United States

Nothing until now

I used it for almost one month but nothing yet. I will continue using it for other 1-2 months otherwise I will return it

>> THE DRM LAB replied:
Hi Layla! Thank you for your honest feedback. We understand it can feel discouraging not seeing immediate changes, especially with stubborn dark spots and uneven tone.For many people, visible improvement happens gradually over 8–12 weeks as the skin naturally renews itself over time. Consistency is extremely important with treatments like this, and we encourage you to continue following the recommended schedule.If you ever need support or have questions about your routine, our team is always here to help!

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Nina

Verified Buyer

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United States

Not working, last chance

I have been using the derm pdrn infusion system along for about 2 months, and have not seen any improvement. Very bummed. My skin looks great the day after the treatment but after the swelling goes down, its back to looking the same. I will give it last chance

>> THE DRM LAB replied:
Hi Nina, thank you for sharing your experience. Everyone’s skin responds differently, especially when it comes to uneven skin tone and long-standing discoloration.Many users notice early improvements in skin texture and radiance first, while visible fading of dark spots can take longer and often requires a full 3-month cycle of consistent treatments.We truly appreciate you giving the system a fair try, and if you need anything at all, our support team is always happy to help.

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Eddie

Verified Buyer

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United States

Never got the product

Was excited to try it but product was not delivered even after a month and payment was taken immediately. Ridiculous that I’m being asked for feedback

>> THE DRM LAB replied:
Hi Eddie, upon checking with our team we never received any email from you. That being said, we apologize for what happened and we just sent you a new product totally for free. We will keep you updated about your shipping. Thank you